Ana Catalina Alvarez-Elías, MD, MSc, PhD.Sc

Ana Catalina Alvarez-Elías

Ana Catalina graduated from pediatric nephrology, followed by a master’s and a Ph.D. degree in Medical Sciences at the Universidad Nacional Autónoma de México. She completed a fellowship in pediatric kidney transplantation at the Transplant & Regenerative Medicine Centre in the Hospital for Sick Children, Toronto, continuing with a combined clinical/research training in nephrology dialysis and transplantation at the same institution.

She is currently a Research Scientist at the Translational Clinical Research in the Renal Research Institute; an international Associate Professor of Pediatric Nephrology and Research in the Dirección de Invetigación Clínica at the Hospital Infantil de México, Federico Gómez; and an invited international professor in the Pediatric Nephrology fellowship program and Centro de Investigaciones Renales at the Fundación para el Niño Enfermo Renal (FUNDANIER), Hospital Roosevelt in Guatemala. She is the Co-Chair of Clinical and Epidemiological Research at the Asociación Latinoamericana de Nefrología Pediátrica (ALANEPE) and an active communications/social media committee member. Ana Catalina is also working to obtain a clinical epidemiology doctoral degree at the Institute of Health Policy Management and Evaluation, University of Toronto. Her research has focused on pharmacogenetics, pharmacoepidemiology, chronic kidney disease, kidney replacement therapies, and healthcare transition readiness to adulthood, targeting personalized medicine, developing translational research, and testing complex statistical models.

Ana Catalina aims to improve healthcare, academics, and research on patients and families dealing with kidney conditions, focusing on the disadvantaged population by building local capacities and dynamic, affordable tools for targeting equitable precision medicine.

Recent Articles by Ana Catalina Alvarez-Elías, MD, MSc, PhD.Sc

  • Current opinion in nephrology and hypertension
    October 6, 2023
    Climate change and its influence in nephron mass
    Ana Catalina Alvarez-Elias, Barry M Brenner, Valerie A Luyckx
    PURPOSE OF REVIEWThe consequences of climate change, including heat and extreme weather events impact kidney function in adults and children. The impacts of climate change on kidney development during gestation and thereby on kidney function later in life have been poorly described. Clinical evidence is summarized to highlight possible associations between climate change and nephron mass.SUMMARYClimate change has important impacts on pregnant women and their unborn children. Being born too small or too soon is associated with life-time risk of kidney disease. Climate change may therefore have a dual effect of impacting fetal kidney development and contributing to cumulative postnatal kidney injury. The impact on population kidney health of future generations may be significant.RECENT FINDINGSPregnant women are vulnerable to the effects of climate change, being less able to thermoregulate, more sensitive to the effects of dehydration, and more susceptible to infections. Exposure to heat, wildfire smoke, drought, floods and climate-related infections are associated with low birth weight, preterm birth and preeclampsia. These factors are associated with reduced nephron numbers, kidney dysfunction and higher blood pressures in offspring in later life. Exposure to air pollution is associated with higher blood pressures in children and has variable effects on estimated glomerular filtration rate.